Best SARM MK677 - What are the benefits of MK677

 

Raw Ibutamoren Mesylate (MK677) powder (159752-10-0) Specifications

Product Name	Raw MK677 powder
Chemical Name	MK-677;2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4′-piperidin]-1′-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate;
Brand Name	Ibutamoren Mesylate（MK677）
Drug Class	MK677 powder
CAS Number	159752-10-0
InChIKey	DUGMCDWNXXFHDE-VZYDHVRKSA-N
Molecular Formula	C27H36N4O5S.CH4O3S
Molecular Weight	624.768 g/mol
Monoisotopic Mass	624.229 g/mol
Melting Point	161 to 315ºC
Boiling Point	868.9 °c at 760 mmhg
Biological Half-Life	4-6 hours
Color	white to beige powder
Solubility	H2O: soluble5mg/mL, clear
Storage Temperature	2-8°C
Ibutamoren Mesylate Application	Growth hormone releasing factor; alters metabolism of body fat; increase both muscle mass and bone mineral density; alters metabolism of body fat

 

MK677 Overview

Raw Ibutamoren Mesylate (MK677) powder is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. MK-677 powder also alters metabolism of body fat and so may have application in the treatment of obesity.

 

Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0) Description

Ibutamoren mesylate (also known as ibutamoren or MK677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1).

Ibutamoren mesylate increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren mesylate may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren mesylate has on appetite – and as expected, like ghrelin, ibutamoren mesylate increases it.

A great thing about ibutamoren mesylate is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0) Mechanism of Action

Ibutamoren mesylate (also known as ibutamoren or MK-677), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1).

Ibutamoren mesylate increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren mesylate may also affect these functions. However, so far, clinical studies describe only the effects ibutamoren mesylate has on appetite – and as expected, like ghrelin, ibutamoren mesylate increases it.

A great thing about ibutamoren mesylate is that it increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

Benefits of Raw Ibutamoren Mesylate (MK677) powder ( 159752-10-0)

♦ MK677 May Help with Bone Density

♦ MK677 May Help Increase Muscle Growth

♦ MK677 May Help Decrease Muscle Wasting

♦ MK677 May Help with Sleep

♦ MK 677 May Reduce the Effects of Aging

♦ MK677 May Have Nootropic Effects on the Brain

Recommended MK677) powder (159752-10-0) Dosage

Based on the research, 20 to 30mg seems to be the most optimal dosage. There are reports of people taking more than 30mg of MK677 a day, but it did not yield in better results. What’s even more important than the dosage is the length of the cycle.

It’s extremely important that MK677 should be taken for a longer period of time. The growth hormone levels have to gradually build up in your body, which can take up to several weeks before you start feeling the effects.

Side effects of MK677 (159752-10-0)

MK677 has not produced very many side effects for its users to be concerned about, but certain populations may have certain side effects to look out for. Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK677. Symptoms associated with these conditions could possibly be exacerbated by the use of MK677. Referring to a previously mentioned study, older individuals who had a previous heart condition are at a risk of heart failure when using MK677. In otherwise healthy individuals, there does not seem to be any harmful side effects that have been discovered, but further research is always needed to assure consumers of that.